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About the Research

Understanding MS and Bone Health

The research I will be involved with is connected to STRONG-MS, a clinician led study focused on improving bone health, muscle strength, physical function, and quality of life in people with multiple sclerosis. MS is a chronic neurological disease that can affect movement, balance, cognition, and overall independence. Globally, more than 1.8 million people live with MS, with many experiencing symptoms that directly interfere with daily function.

The Musculoskeletal Connection

This work matters because MS does not only affect the nervous system. It can also create a serious musculoskeletal problem. People with MS often have lower physical activity levels, muscle weakness, impaired balance, vitamin D deficiency, corticosteroid exposure, and reduced bone mineral density. Together, these factors increase the risk of falls and fractures alike. With Recent evidence suggests that people with MS have about a twofold higher risk of osteopenia, a 1.7-fold higher risk of osteoporosis, and a 1.9-fold higher risk of fracture compared with healthy controls.

The STRONG-MS Study

The STRONG-MS study is testing whether a structured high-intensity resistance and impact training intervention can be safe and effective for people with MS across different symptom profiles. The study examines outcomes such as bone mineral density, muscle strength, physical function, and health-related quality of life.

Translational Goals & Strategy

The larger goal is translational: to move from knowing that bone and muscle decline are problems in MS to developing exercise-based strategies that clinicians can realistically use. If this type of intervention is shown to be feasible and beneficial, it could help shape future rehabilitation programs, redumprove independence for people living with MS. 

Preserving Independence Through Science

Reflections

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